There are always people and organizations researching the treatment and prevention of all types of cancer, including mesothelioma. Here’s an update on the research. There seem to be some promising treatments on the way.
New Drugs
Chemotherapy drugs have not been as effective against advanced mesothelioma as we have hoped. Several new drugs are being studied. Among them are:
Anti-growth factor drugs – These drugs aim to kill cancer cells by depriving them of blood. A drug of this type that is currently available is Bevacizumab (Avastin). It is approved for the treatment of colorectal cancer, and is being tested for effectiveness in combating mesothelioma.
Anti-angiogenesis drugs – These drugs aim to hinder cancer cells’ production of substances that stimulate their growth. Erlotinib (Tarceva) is one such drug
For information on clinical trials for Avastin and Tarceva for the treatment of mesothelioma, click here.
Belinostat (PXD101) – This drug represents a new “class of anti-cancer therapeutics that target HDAC enzymes that have been shown to: arrest growth of cancer cells (including drug resistant subtypes); induce … programmed cell death; promote differentiation, inhibit angiogenesis; and sensitize cancer cells to overcome drug resistance when used in combination with other anti-cancer agents,” according to the drug maker’s press release.
This drug has showed promising results in preliminary studies and will continue to be tested. More details here.
Gene Therapy – In this approach, special lab-modified viruses are injected into the space between the pleural mesothelioma and the chest cavity lining. The viruses then attack the mesothelioma cells and inject a gene into them that may help the body’s immune system recognize the cells as a threat and attack them.
For information on gene therapy clinical trials, cick here.